Infection-Related Glomerulonephritis: Changing Demographics and Outcomes
Advances In Chronic Kidney Disease , 04/09/2012
Nast CC – Organisms causing postinfectious glomerulonephritis (PIGN) are also changing, with fewer cases associated with Streptococcus and more cases owing to Staphylococcus. IgA–dominant PIGN has become more widely recognized as a lesion usually found in adult patients with diabetes or another form of chronic illness, with more severe clinical manifestations and a more guarded outcome. Children have the best prognosis and outcome followed by healthy adults, with adults having comorbid factors exhibiting more chronic renal injury following PIGN.