The placebo effect in overactive bladder syndrome
Nature Reviews Urology, 07/11/2011
Mangera A et al. – Overactive bladder syndrome (OAB) is a condition that involves urinary urgency and affected individuals are usually treated with behavioral therapy and antimuscarinic agents as first–line therapies. Existing evidence from clinical trial data suggests that a positive placebo effect occurs in patients receiving treatment for OAB. In the systematic Review of placebo–controlled, randomized trials in OAB, authors show statistically significant improvements in three patient–reported outcomes—incontinence episodes per day, micturition episodes per day and mean micturition volume from baseline–after placebo in randomized studies for OAB.