Protein expression and gene promoter hypermethylation of CD99 in transitional cell carcinoma of urinary bladder
Journal of Cancer Research & Clinical Oncology, 03/18/2010
Xuan Y et al. – The down–regulation of CD99 protein expression is a critical event in the progress of TCC, especially in advanced stage, and it can be explained by the presence of CD99 gene promoter hypermethylation in TCC. And both CD99 protein expression and gene promoter hypermethylation have clinical significance and implication for the diagnosis and target therapy for TCC.







