Urology - Oncology News & Articles

Now available on MDLinx Urology, find daily updates summarizing the top literature from over 2,000 peer-reviewed journals, including Journal of Urology, European Urology, The Prostate, and more. Find coverage of the kidney, bladder, penis/urethra and prostate. View article summaries by subspecialty and disease state, including peds urology, urologic oncology, stone disease, infections and STDs, urologic imaging, ureteral disease, voiding and incontinence, infertility, laparoscopy and other surgical techniques, and additional hot topics in your field. Find exclusive content only available on MDLinx Urology like articles highlighted by physician editor D. Scott Cunningham, MD, PhD, and clinical pearls gleaned from The Smartest Doc quiz competitions and Physician Reviews.

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Latest (11) Full Text Articles (345)

Ranked, sorted, and summarized by MDLinx editors from the latest literature

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41 Knockdown of Regulator of Cullins-1 (ROC1) Expression Induces Bladder Cancer Cell Cycle Arrest at the G2 Phase and Senescence PLOS ONE, May 15, 2013 Review Article

42 Effect of Small Molecules Modulating Androgen Receptor (SARMs) in Human Prostate Cancer Models PLOS ONE, May 15, 2013 Review Article

43 Model-based patterns in prostate cancer mortality worldwide British Journal of Cancer, May 14, 2013 Clinical Article

44 Evaluation and validation of the Core Lower Urinary Tract Symptom Score as an outcome assessment tool for the treatment of benign prostatic hyperplasia: Effects of the 1-adrenoreceptor antagonist silodosin International Journal of Urology, May 14, 2013 Clinical Article

45 1.5-t magnetic resonance-guided transgluteal biopsies of the prostate in patients with clinically suspected prostate cancer: technique and feasibility Investigative Radiology, May 14, 2013 Clinical Article

46 The link between benign prostatic hyperplasia and sexual dysfunction Current Bladder Dysfunction Reports, May 14, 2013 Review Article

47 The association between overall survival of prostate cancer patients and hypertension, hyperglycemia, and overweight in Southern China: a prospective cohort study Journal of Cancer Research & Clinical Oncology, May 14, 2013 Clinical Article

48 High Circulating Estrogens and Selective Expression of ER{beta} in Prostate Tumors: Implications for Racial Disparity of Prostate Cancer Carcinogenesis, May 14, 2013 Clinical Article

49 Interactional expression of netrin-1 and its dependence receptor UNC5B in prostate carcinoma Tumor Biology, May 14, 2013 Clinical Article

50 Independent prognostic factors for initial intravesical recurrence after laparoscopic nephroureterectomy for upper urinary tract urothelial carcinoma Urologic Oncology: Seminars and Original Investigations, May 14, 2013 Clinical Article

51 Inhibition of presenilins attenuates proliferation and invasion in bladder cancer cells through multiple pathways Urologic Oncology: Seminars and Original Investigations, May 14, 2013 Clinical Article

52 Treating octogenarians with muscle-invasive bladder cancer: Preoperative opportunities for increasing the benefits of surgical intervention Urologic Oncology: Seminars and Original Investigations, May 14, 2013 Review Article

53 Biopsy-proven brain metastases from prostate cancer: a series of four cases with review of the literature International Urology and Nephrology, May 14, 2013

54 The number of nodes removed as well as the template of the dissection is independently correlated to cancer-specific survival after radical cystectomy for muscle-invasive bladder cancer International Urology and Nephrology, May 14, 2013 Review Article

55 Percutaneous nephrostomy for ureteric obstruction due to advanced pelvic malignancy: have we got the balance right International Urology and Nephrology, May 14, 2013 Review Article

56 Renal rhabdomyosarcoma in a pancake kidney Urology, May 14, 2013

57 Image-directed, tissue-preserving focal therapy of prostate cancer: a feasibility study of a novel deformable MR-US registration system BJU International, May 13, 2013 Clinical Article

58 Optimization of initial prostate biopsy in clinical practice: sampling, labeling and specimen processing The Journal of Urology, May 13, 2013 Review Article

59 Immunohistochemical expression of ERG in the molecular epidemiology of fatal prostate cancer study The Prostate, May 13, 2013 Clinical Article

60 Ericifolin: a novel antitumor compound from allspice that silences androgen receptor in prostate cancer Carcinogenesis, May 13, 2013 Clinical Article

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Clinical Pearls in Urology

Because temozolomide is associated with changes in male fertility, consider referring patients for sperm banking prior to initiating chemotherapy for glioblastoma multiforme (GBM)
The schedule of radium-223 used in the ALSYMPCA trial is 5 minute infusion every 4 weeks x6 doses. Given in this fashion, it significantly improved median OS, time to SRE and time to PSA progression in men with advanced cancer of the prostate without demonstrable side effects
In RTOG 94-08 the addition of short course androgen deprivation to radiation therapy for men with intermediate risk cancer of the prostate resulted in a 50% reduction in disease specific mortality at 10-years

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Highlights in Urology

Red meat cooked at high temperatures increases risk of advanced cancer of the prostate

Researchers at the University of Southern California have reported a risk between advanced cancer of the prostate and red meats cooked at high temperature, pan-frying, and prepared "well done." The study involved 1140 men with advanced cancer of the prostate, 717 men with localized cancer of the prostate, and 1096 healthy controls from the California Collaborative Prostate Cancer Study. There was an inverse association between baked poultry and advanced prostate cancer.

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Risk factors for delirium post-radical cystectomy

Researchers at the University of Chicago Pritzker School of Medicine have reported that older age and the pre-operative MMSE results are associated with post-radical cystectomy (OR = 1.52) in patients > 65 years of age (n=49). The incidence of post-operative delirium was 29%. Further, patients with post-operative delirium were at increased risk for readmission (OR = 10.7) and re-operation (OR = 9.2).

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PSA screening reduces risk of metastatic cancer of the prostate

As published in European Neurology, men (age range, 55-69 years) who undergo PSA screening are at decreased risk for metastatic cancer of the prostate. The study involved 76,813 men with a median follow-up of 12 y. There were 666 cases with metastatic cancer of the prostate(256 screened [.67%/1000] and 410 non-screened [.86%/1000]). The HR for men who were screened was 0.58.

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Last month's top read Top Articles of 2012

1 Androgen annihilation as a new therapeutic paradigm in advanced prostate cancer Current Opinion in Urology, April 8, 2013 Review Article

2 Low serum testosterone levels are predictive of prostate cancer World Journal of Urology, April 9, 2013

3 Early versus deferred androgen suppression therapy for patients with lymph node-positive prostate cancer after local therapy with curative intent: a systematic review BMC Cancer, March 21, 2013 Free full text Evidence Based Medicine Review Article

4 Morbidity of focal therapy in the treatment of localized prostate cancer European Urology, April 1, 2013 Free full text

5 Six-month leuprorelin acetate depot formulations in advanced prostate cancer: a clinical evaluation Clinical Interventions in Aging, April 29, 2013 Free full text

6 Minireview: Androgen Metabolism in Castration-Resistant Prostate Cancer Molecular Endocrinology, April 17, 2013 Review Article

7 Associations of tea and coffee consumption with prostate cancer risk Cancer Causes and Control, April 22, 2013

8 A randomized clinical study to compare the efficacy and safety of naftopidil versus tamsulosin in symptomatic benign prostatic hyperplasia UroToday International Journal, April 3, 2013
Exclusive Author Commentary

9 Consideration of comorbidity in risk stratification prior to prostate biopsy Cancer, April 26, 2013

10 Surgical castration for androgen-deprivation therapy of prostate cancer – relevance in current practice Journal of Clinical Urology, April 2, 2013

11 Do patients with metastatic urothelial carcinoma benefit from docetaxel as second-line chemotherapy Clinical and Translational Oncology, April 24, 2013

12 Impact of smoking and smoking cessation on oncologic outcomes in primary non–muscle-invasive bladder cancer European Urology, March 27, 2013 Free full text

13 Prostate volume as an independent predictor of prostate cancer in men with PSA of 10-50 ng ml^-1 Asian Journal of Andrology, April 24, 2013

14 Hypofractionated external-beam radiation therapy (HEBRT) versus conventional external-beam radiation (CEBRT) in patients with localized prostate cancer: a systematic review and meta-analysis Core Evidence, March 18, 2013

15 Prostate cancer prevention: strategies for agent development Current Opinion in Oncology, April 16, 2013 Review Article

16 Phase III, randomized, placebo-controlled study of docetaxel in combination with zibotentan in patients with metastatic castration-resistant prostate cancer Journal of Clinical Oncology, April 10, 2013

17 Prevalence of patients with nonmetastatic prostate cancer on androgen deprivation therapy in the United States Urology, April 19, 2013

18 Zinc and zinc transporters in prostate carcinogenesis Nature Reviews Urology, March 13, 2013

19 Statin use and risk of prostate cancer and high-grade prostate cancer: results from the REDUCE study Prostate Cancer & Prostatic Diseases, April 11, 2013

20 Is lycopene an effective agent for preventing prostate cancer? Cancer Prevention Research, March 14, 2013 Review Article

Indexed Journals in Urology: Urology, Journal of Urology, European Urology, The Prostate more

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Urology - Oncology News & Articles

Articles

Clinical Pearls in Urology

Highlights in Urology

Red meat cooked at high temperatures increases risk of advanced cancer of the prostate

Risk factors for delirium post-radical cystectomy

PSA screening reduces risk of metastatic cancer of the prostate

Most Popular Urology Articles

Other Topics in Urology