Urology - Prostate News & Articles

Now available on MDLinx Urology, find daily updates summarizing the top literature from over 2,000 peer-reviewed journals, including Journal of Urology, European Urology, The Prostate, and more. Find coverage of the kidney, bladder, penis/urethra and prostate. View article summaries by subspecialty and disease state, including peds urology, urologic oncology, stone disease, infections and STDs, urologic imaging, ureteral disease, voiding and incontinence, infertility, laparoscopy and other surgical techniques, and additional hot topics in your field. Find exclusive content only available on MDLinx Urology like articles highlighted by physician editor D. Scott Cunningham, MD, PhD, and clinical pearls gleaned from The Smartest Doc quiz competitions and Physician Reviews.

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Latest (10) Full Text Articles (290)

Ranked, sorted, and summarized by MDLinx editors from the latest literature

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1 Differences in prostate cancer detection rates according to the level of glomerular filtration rate in patients with prostate specific antigen levels of 4.0-10.0 ng/ml International Journal of Clinical Practice, May 24, 2013 Clinical Article

2 Patient demographics, quality of life, and disease features of men with newly diagnosed prostate cancer: trends in the PSA era Urology, May 24, 2013 Clinical Article

3 Quantitative analysis of multiparametric prostate mr images: differentiation between prostate cancer and normal tissue and correlation with gleason score—a computer-aided diagnosis development study Radiology, May 24, 2013 Clinical Article

4 NF-kappaB2/p52 induces resistance to enzalutamide in prostate cancer: role of androgen receptor and its variants Molecular Cancer Therapeutics, May 24, 2013 Clinical Article

5 Genome-wide methylation analysis of prostate tissues reveals global methylation patterns of prostate cancer American Journal of Pathology, May 24, 2013 Clinical Article

6 Changes in S-PSA after transurethral resection of prostate and its correlation to postoperative outcome International Urology and Nephrology, May 24, 2013 Review Article

7 Androgen receptor roles in the development of benign prostate hyperplasia American Journal of Pathology, May 24, 2013 Review Article

8 Genomic profiling defines subtypes of prostate cancer with the potential for therapeutic stratification Clinical Cancer Research, May 24, 2013 Review Article

9 The loss of the tumour-suppressor miR-145 results in the shorter disease-free survival of Prostate cancer patients British Journal of Cancer, May 24, 2013 Clinical Article

10 Brassinin induces apoptosis in pc-3 human prostate cancer cells through the suppression of pi3k/akt/mtor/s6k1 signaling cascades Phytotherapy Research, May 24, 2013 Review Article

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11 Clinical performance of serum isoform [-2]propsa (p2psa) and its derivatives, namely %p2psa and phi (prostate health index), in men with a family history of prostate cancer. Results from a multicentre European study (prometheus project) BJU International, May 23, 2013 Clinical Article

12 Using the epigenetic field defect to detect prostate cancer in biopsy negative patients The Journal of Urology, May 23, 2013 Clinical Article

13 Relationship of gleason patterns in gleason score 7 prostate cancer Cancer Research, May 23, 2013 Clinical Article

14 Causes of death in men with prostate cancer: an analysis of 50,000 men from the thames cancer registry BJU International, May 23, 2013 Clinical Article

15 ETS transcription factor ESE1/ELF3 orchestrates a positive feedback loop that constitutively activates NF-kB and drives prostate cancer progression. Cancer Research, May 23, 2013 Clinical Article

16 Impact of a nurse-run clinic on prevalence of urinary incontinence and everyday life in men undergoing radical prostatectomy Journal of Wound, Ostomy, and Continence Nursing, May 23, 2013 Clinical Article

17 Cardiovascular risk factors among long-term survivors of breast, prostate, colorectal, and gynecologic cancers: a gap in survivorship care? Journal of Cancer Survivorship, May 23, 2013 Review Article

18 Prognostic potential of ERG (ETS-related gene) expression in prostatic adenocarcinoma International Urology and Nephrology, May 23, 2013 Review Article

19 A comparison of prostate cancer diagnosis in patients receiving unrelated urologic and non-urologic cancer care BJU International, May 23, 2013 Clinical Article

20 Cardiovascular risk and bone loss in men undergoing androgen deprivation therapy for non-metastatic prostate cancer: implementation of standardized management guidelines Journal of Andrology, May 22, 2013 Clinical Article

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Clinical Pearls in Urology

Because temozolomide is associated with changes in male fertility, consider referring patients for sperm banking prior to initiating chemotherapy for glioblastoma multiforme (GBM)
The schedule of radium-223 used in the ALSYMPCA trial is 5 minute infusion every 4 weeks x6 doses. Given in this fashion, it significantly improved median OS, time to SRE and time to PSA progression in men with advanced cancer of the prostate without demonstrable side effects
In RTOG 94-08 the addition of short course androgen deprivation to radiation therapy for men with intermediate risk cancer of the prostate resulted in a 50% reduction in disease specific mortality at 10-years

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Highlights in Urology

Red meat cooked at high temperatures increases risk of advanced cancer of the prostate

Researchers at the University of Southern California have reported a risk between advanced cancer of the prostate and red meats cooked at high temperature, pan-frying, and prepared "well done." The study involved 1140 men with advanced cancer of the prostate, 717 men with localized cancer of the prostate, and 1096 healthy controls from the California Collaborative Prostate Cancer Study. There was an inverse association between baked poultry and advanced prostate cancer.

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Risk factors for delirium post-radical cystectomy

Researchers at the University of Chicago Pritzker School of Medicine have reported that older age and the pre-operative MMSE results are associated with post-radical cystectomy (OR = 1.52) in patients > 65 years of age (n=49). The incidence of post-operative delirium was 29%. Further, patients with post-operative delirium were at increased risk for readmission (OR = 10.7) and re-operation (OR = 9.2).

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PSA screening reduces risk of metastatic cancer of the prostate

As published in European Neurology, men (age range, 55-69 years) who undergo PSA screening are at decreased risk for metastatic cancer of the prostate. The study involved 76,813 men with a median follow-up of 12 y. There were 666 cases with metastatic cancer of the prostate(256 screened [.67%/1000] and 410 non-screened [.86%/1000]). The HR for men who were screened was 0.58.

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Last month's top read Top Articles of 2012

1 Statin use and risk of prostate cancer and high-grade prostate cancer: results from the REDUCE study Prostate Cancer & Prostatic Diseases, April 11, 2013

2 Surgical castration for androgen-deprivation therapy of prostate cancer – relevance in current practice Journal of Clinical Urology, April 2, 2013

3 Prostate cancer prevention: strategies for agent development Current Opinion in Oncology, April 16, 2013 Review Article

4 Prostate volume as an independent predictor of prostate cancer in men with PSA of 10-50 ng ml^-1 Asian Journal of Andrology, April 24, 2013

5 Contemporary practice patterns of endoscopic surgical management for benign prostatic hyperplasia among urologists in the United States The Journal of Urology, April 18, 2013

6 Consideration of comorbidity in risk stratification prior to prostate biopsy Cancer, April 26, 2013

7 Low serum testosterone levels are predictive of prostate cancer World Journal of Urology, April 9, 2013

8 Associations of tea and coffee consumption with prostate cancer risk Cancer Causes and Control, April 22, 2013

9 Prevalence of patients with nonmetastatic prostate cancer on androgen deprivation therapy in the United States Urology, April 19, 2013

10 Phase III, randomized, placebo-controlled study of docetaxel in combination with zibotentan in patients with metastatic castration-resistant prostate cancer Journal of Clinical Oncology, April 10, 2013

11 Factors associated with reduction in use of neoadjuvant androgen suppression therapy before radical prostatectomy Urology, March 29, 2013

12 Improving risk stratification in patients with prostate cancer managed by active surveillance: a nomogram predicting the risk of biopsy progression BJU International, April 12, 2013

13 A dose-ranging study of cabozantinib in men with castration-resistant prostate cancer and bone metastases Clinical Cancer Research, April 4, 2013

14 Is the use of empiric antibiotics for elevated prostate specific antigen a risk factor for infectious complications after transrectal ultrasound-guided prostate biopsy Urology Times, April 29, 2013

15 Morbidity of focal therapy in the treatment of localized prostate cancer European Urology, April 1, 2013 Free full text

16 A prospective randomized trial of povidone-iodine prophylactic cleansing of the rectum before transrectal ultrasound guided prostate biopsy The Journal of Urology, April 8, 2013

17 Importance and determinants of Gleason score undergrading on biopsy sample of prostate cancer in a population-based study BMC Urology, April 15, 2013 Free full text

18 Randomized controlled trial to assess the efficacy of the combination therapy of alfuzosin and tadalafil in patients with lower urinary tract symptoms due to benign prostatic hyperplasia LUTS: Lower Urinary Tract Symptoms, April 5, 2013

19 Screening for Prostate Cancer: A Guidance Statement From the Clinical Guidelines Committee of the American College of Physicians Annals of Internal Medicine, April 10, 2013 Clinical Guideline

20 A randomized clinical study to compare the efficacy and safety of naftopidil versus tamsulosin in symptomatic benign prostatic hyperplasia UroToday International Journal, April 3, 2013
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Urology - Prostate News & Articles

Articles

Prior Articles

Clinical Pearls in Urology

Highlights in Urology

Red meat cooked at high temperatures increases risk of advanced cancer of the prostate

Risk factors for delirium post-radical cystectomy

PSA screening reduces risk of metastatic cancer of the prostate

Most Popular Urology Articles

Other Topics in Urology