Urology News Articles

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Search today's latest Urology news articles updated daily summarizing the most recent top clinical literature from over 2,000 peer-reviewed journals, including Journal of Urology, European Urology, The Prostate, and more. Read coverage of the kidney, bladder, penis/urethra and prostate. View article summaries by subspecialty and disease state, including pediatric urology, urologic oncology, kidney stone disease, infections and STDs, urologic imaging, ureteral disorders, voiding and incontinence, infertility, laparoscopy and other surgical techniques in Urology.

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Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Upper limit of cancer extent on biopsy defining very low risk prostate cancer BJU International, July 25, 2014    Clinical Article

2 Population-based analysis of treatment modalities and survival for clinically localized small-cell carcinoma of the prostate Prostate Cancer & Prostatic Diseases, July 25, 2014    Clinical Article

3 Development of clinical models for predicting erectile function after localized prostate cancer treatment International Journal of Urology, July 25, 2014    Clinical Article

4 Clinical activity of enzalutamide versus docetaxel in men with castration-resistant prostate cancer progressing after abiraterone The Prostate, July 25, 2014    Clinical Article

5 Inhibition of the androgen receptor by mineralocorticoids at levels physiologically achieved in serum in patients treated with abiraterone acetate Prostate Cancer & Prostatic Diseases, July 25, 2014    Clinical Article

6 Comparative effects of two different forms of selenium on oxidative stress biomarkers in healthy men: a randomized clinical trial Cancer Prevention Research, July 25, 2014    Clinical Article

7 Evidence for molecular differences in prostate cancer between African American and Caucasian men Clinical Cancer Research, July 25, 2014    Clinical Article

8 Transvesical robotic simple prostatectomy: Initial clinical experience Full Text European Urology, July 25, 2014    Clinical Article

9 Prostatic urethral angle might be a predictor of treatment efficacy of α-blockers in men with lower urinary tract symptoms Full Text Drug Design, Development and Therapy, July 25, 2014    Clinical Article

10 Gleason score 3 + 4=7 prostate cancer with minimal quantity of Gleason pattern 4 on needle biopsy is associated with low-risk tumor in radical prostatectomy specimen American Journal of Surgical Pathology , July 25, 2014    Clinical Article

11 Improving the clinical prediction of detrusor overactivity by utilizing additional symptoms and signs to overactive bladder symptoms alone International Urogynecology Journal, July 25, 2014    Clinical Article

12 Grading of evidence for bladder pain syndrome: A comparative review of study quality assessment methods International Urogynecology Journal, July 25, 2014    Review Article    Clinical Guideline

13 The economics of bladder cancer: Costs and considerations of caring for this disease Full Text European Urology, July 25, 2014    Review Article

14 Ultrasound assessment of urethral support in women with stress urinary incontinence during and after first pregnancy Obstetrics and Gynecology, July 25, 2014    Clinical Article

15 Sexual dysfunction at the onset of type 2 diabetes: The interplay of depression, hormonal and cardiovascular factors The Journal of Sexual Medicine, July 25, 2014    Clinical Article

16 Detrusor contraction power parameters (BCI and Wmax) rise with increasing bladder outlet obstruction grade in men with lower urinary tract symptoms: Results from a urodynamic database analysis World Journal of Urology, July 25, 2014    Clinical Article

17 Effectiveness of a program of therapeutic exercises on the quality of life and lumbar disability in women with Stress Urinary Incontinence Journal of Bodywork & Movement Therapies , July 25, 2014    Clinical Article

18 Intraoperative continuous norepinephrine infusion combined with restrictive deferred hydration significantly reduces the need for blood transfusion in patients undergoing open radical cystectomy: Results of a prospective randomized trial Full Text European Urology, July 25, 2014    Clinical Article

19 Understanding men's attributions of why they ejaculate before desired: An internet study The Journal of Sexual Medicine, July 25, 2014    Clinical Article

20 Clinical prognosticators of survival in patients with urothelial carcinoma of the bladder and lymph node metastases after cystectomy with curative intent World Journal of Urology, July 25, 2014    Clinical Article

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Highlights in Urology

GALNT4 predicts survival in patients with ccRCC

As reported in the Journal of Urology, N-acetylgalactosaminyltransferase 4 (GALNT4) levels are decreased in tumor specimens from patients with clear cell renal cell carcinoma (ccRCC; n=104) compared to peritumoral specimens. Decreased expression of GALNT4 is associated with poor OS (OR=3.08) and RFS (OR=2.17). Further, GALNT4 is negatively correlated with tumor size, necrosis, and TNM stage.

3-month PSA is a predictor of BCR-free survival after radical prostatectomy

As reported in the International Journal of Clinical Oncology, the 5-year biochemical recurrence (BCR)-free survival rate is significantly higher in patients with a 3-month PSA level < 0.010 ng/ml compared to patients with a 3-month PSA level between 0.010 and 100 ng/ml (92.6% vs. 57.4%). Amongst 174 men who underwent radical prostatectomy for clinically localized prostate cancer, 18.4% had a BCR and the median time to BCR was 16 months.

Chromogranin A staining as a biomarker for prostate adenocarcinoma

As reported in The Prostate, chromogranin A (CgA) staining, an indicator of neuroendocrine differentiation, is associated with decreased biochemical control, clinical failure, increased distant metastases, and decreased cause-specific survival in patients with prostate adenocarcinoma and a GS ≥ 7 (n=285). The median follow-up was 6.5 y. CgA staining was present in 31% of specimens. The 10-y distant metastases rate in specimens with <1% and >1% CgA staining was 8% and 48%, respectively. The 10-y cause-specific survival in specimens with <1% and >1% CgA staining was 95% vs. 76%, respectively.

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