The Latest Journal Articles in Urology

1Earlier prostate-specific antigen testing in African American men - Clinical support for the recommendationUrologic Oncology: Seminars and Original Investigations, May 05, 2015  Clinical Article
2Robust inverse-consistent affine CT-MR registration in MRI-assisted and MRI-alone prostate radiation therapyMedical Image Analysis, May 05, 2015  Clinical Article
3Contemporary role of salvage lymphadenectomy in patients with recurrence following radical prostatectomyEuropean Urology, May 05, 2015  Full Text  Review Article
4An antimicrobial prophylaxis protocol using rectal swab cultures for transrectal prostate biopsyWorld Journal of Urology, May 05, 2015  Clinical Article
5Safety and efficacy of iodine-125 permanent prostate brachytherapy in patients with J-pouch anastomosis after total colectomy for ulcerative colitisPractical Radiation Oncology, May 05, 2015  Clinical Article
6Vitamin D3 potentiates the growth inhibitory effects of metformin in DU145 human prostate cancer cells mediated by AMPK/mTOR signaling pathwayClinical and Experimental Pharmacology and Physiology, May 05, 2015  Clinical Article
7Assessment of tamsulosin 0.2 mg for symptomatic bladder outlet obstruction secondary to benign prostatic enlargement: Data from a Korean multicenter cross-sectional studyUrologia Internationalis, May 05, 2015  Clinical Article
8The value of anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic acid PET/CT in the diagnosis of recurrent prostate carcinoma: A meta-analysisActa Radiologica, May 05, 2015  Clinical Article  Evidence Based Medicine  Review Article
9The fractionated dipole antenna: A new antenna for body imaging at 7 TeslaMagnetic Resonance in Medicine, May 05, 2015  Clinical Article
1New combination therapy effective even for larger prostate cancersMedical University of Vienna, May 04, 2015
2Boosting the body's natural ability to fight urinary tract infectionsUC San Diego Health System, May 04, 2015
3Advanced viral gene therapy eradicates prostate cancer in preclinical experimentsVirginia Commonwealth University News, May 04, 2015
4Combined chemotherapy and immunotherapy shows promise for advanced prostate cancersUC San Diego Health System, May 01, 2015
5Urine profiles provide clues to how obesity causes diseaseImperial College London Health News, May 01, 2015
6Subgroup of men with metastatic prostate cancer responded to olaparib treatmentAmerican Association for Cancer Research News, April 30, 2015
7As circumcision wounds heal, HIV-positive men may spread virus to female partners, study showsJohns Hopkins Medicine, April 30, 2015
8It's Your Game-Tech increases teens' knowledge about STIs, condomsUniversity of Texas Health Science Center at Houston News, April 30, 2015
9After prostate cancer, start walkingNorthwestern University News, April 29, 2015
10Little red 'superfruit' helps ward off common infectionUniversity of Michigan Regents News, April 29, 2015

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PCA3 useful for early diagnosis of prostate cancer

Based on a meta-analysis reported in the Chinese Medical Journal, prostate cancer antigen 3 (PCA3) can be used for the early diagnosis of prostate cancer and to avoid unnecessary biopsies, with a sensitivity of 0.82, a specificity of 0.962, a positive likelihood ratio of 2.39, a negative likelihood ratio of 0.51, and a diagnostic odds ratio of 4.89.

High expression of MUC1 + HER3 is associated with favorable outcome in bladder cancer patients

As reported in BJU International, elevated co-expression of MUC1 + HER3 was associated with improved survival in patients with bladder cancer. MUC1 alone, or elevated MUC1 + non-elevated HER3, had no prognostic value. Moreover, MUC1 was not predictive of survival, tumor stage, or tumor grade.

GALNT4 predicts survival in patients with ccRCC

As reported in the Journal of Urology, N-acetylgalactosaminyltransferase 4 (GALNT4) levels are decreased in tumor specimens from patients with clear cell renal cell carcinoma (ccRCC; n=104) compared to peritumoral specimens. Decreased expression of GALNT4 is associated with poor OS (OR=3.08) and RFS (OR=2.17). Further, GALNT4 is negatively correlated with tumor size, necrosis, and TNM stage.

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