Pathologic Downstaging Is a Surrogate Marker for Efficacy and Increased Survival Following Neoadjuvant Chemotherapy and Radical Cystectomy for Muscle-Invasive Urothelial Bladder Cancer

European Urology, 06/01/2012

Survival benefits of neoadjuvant chemotherapy are reflected in downstaging of the primary tumour. Chemo–induced downstaging might be a potential surrogate marker for overall survival.

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