Second Multicenter, Randomized, Double-blind, Parallel-group Evaluation of Effectiveness and Safety of Intravesical Sodium Chondroitin Sulfate Compared With Inactive Vehicle Control in Subjects With Interstitial Cystitis/Bladder Pain Syndrome
Nickel JC et al. – Intravesical chondroitin sulfate therapy for interstitial cystitis/bladder pain syndrome (IC/BPS) might result in minor improvements in IC/BPS–related symptom and pain. However, the magnitude of benefit in the authors' small pilot study does not support its use as monotherapy for this condition. Better strategies for selecting patients with a bladder–specific clinical phenotype might improve the overall response to this type of intravesical therapy.