Third-Generation Salvage Cryotherapy for Radiorecurrent Prostate Cancer: A Centre’s Experience
Urologia Internationalis, 03/29/2012
Philippou P et al. – The relatively high rates of biochemical response support the use of cryotherapy as a salvage procedure for radiorecurrent prostate cancer.Methods
- Between February 2006 and August 2008, 19 patients underwent salvage cryotherapy for radiorecurrent prostate cancer.
- Post-radiotherapy recurrence was confirmed by prostatic biopsy.
- The ‘Phoenix definition’ was used to define biochemical failure after salvage cryotherapy.
- The mean age at cryotherapy was 69.2 years and the mean time from radiotherapy to cryotherapy was 72.3 months.
- Patient characteristics prior to cryotherapy included a mean PSA level of 6.84 ng/ml and a median Gleason score of 7.
- The mean post-cryotherapy follow-up was 33.3 months.
- The 2-year biochemical disease-free survival rate was 58%.
- The median post-cryotherapy PSA nadir was 0.20 ng/ml (range 0.005–8.260).
- There were no procedure-related or cancer-related deaths.