Alterations of microbiota in urine from women with interstitial cystitis

BMC Microbiology, 09/14/2012

The 16S rDNA sequence data demonstrates a shift in the composition of the bacterial community in Interstitial Cystitis (IC) urine. The reduced microbial diversity and richness is accompanied by a higher abundance of the bacterial genus Lactobacillus, compared to healthy female (HF) urine. This study demonstrates that high throughput sequencing analysis of urine microbiota in IC patients is a powerful tool towards a better understanding of this enigmatic disease.

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