Bilateral paraneoplastic optic neuropathy and unilateral retinal compromise in association with prostate cancer: a differential diagnostic challenge in a patient with unexplained visual loss

Documenta Ophthalmologica, 05/14/2012

The authors report a 77–year–old Caucasian man with a 1–year complaint of unexplained visual loss and a 4–year history of prostate cancer. A complete ophthalmologic exam, Goldmann visual fields, intravenous fluorescein angiography, macular and disc optical coherence tomography, pattern–reversal visual evoked potentials, and flash electroretinograms were performed. Auto–Ab testing in combination with visual function tests helps achieve a better understanding of the pathophysiology of vision loss in paraneoplastic visual syndromes.

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