Down-regulation of calcium/calmodulin-dependent protein kinase kinase 2 by androgen deprivation induces castration-resistant prostate cancer

The Prostate, 05/04/2012

Induction of androgen–hypersensitivity after ADT may be involved in down–regulation of CAMKK2. This result may provide new therapeutic approach to keep androgen–sensitivity of prostate cancer after ADT.

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