Urology News Articles

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Search today's latest Urology news articles updated daily summarizing the most recent top clinical literature from over 2,000 peer-reviewed journals, including Journal of Urology, European Urology, The Prostate, and more. Read coverage of the kidney, bladder, penis/urethra and prostate. View article summaries by subspecialty and disease state, including pediatric urology, urologic oncology, kidney stone disease, infections and STDs, urologic imaging, ureteral disorders, voiding and incontinence, infertility, laparoscopy and other surgical techniques in Urology.

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Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Prostate cancer incidence, clinical stage and survival in relation to obesity: A prospective cohort study in Denmark International Journal of Cancer, October 2, 2014    Clinical Article

2 Chromogranin A is a potential prognostic marker in prostate cancer patients treated with enzalutamide The Prostate, October 2, 2014    Clinical Article

3 Efficacy, patient-reported outcomes (PROS), and tolerability of the changing therapeutic landscape in patients with metastatic prostate cancer (MPC): A systematic literature review Value in Health, October 2, 2014    Review Article

4 Meat and fish consumption and the risk of renal cell carcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC) International Journal of Cancer, October 2, 2014    Clinical Article

5 Investigation of miR-21, miR-141, and miR-221 expression levels in prostate adenocarcinoma for associated risk of recurrence after radical prostatectomy The Prostate, October 2, 2014    Clinical Article

6 Negative predictive value of multiparametric MRI for prostate cancer detection: Outcome of 5-year follow-up in men with negative findings on initial MRI studies European Journal of Radiology, October 2, 2014    Clinical Article

7 Risk of new-onset diabetes after androgen deprivation therapy for prostate cancer in the Asian population Journal of Diabetes, October 2, 2014    Review Article

8 Plk1 inhibition enhances the efficacy of androgen signaling blockade in castration-resistant prostate cancer Cancer Research, October 2, 2014    Clinical Article

9 Muscle and bone effects of androgen deprivation therapy: Current and emerging therapies Endocrine-Related Cancer, October 2, 2014    Review Article

10 The risk of kidney cancer in patients with kidney stones: a systematic review and meta-analysis QJM: An International Journal of Medicine, October 2, 2014    Evidence Based Medicine    Review Article

11 A mimic of sarcomatoid adrenal cortical carcinoma: Epithelioid angiosarcoma occurring in adrenal cortical adenoma Endocrine Pathology, October 2, 2014    Clinical Article

12 Hormonal therapy using gonadotropin releasing hormone for improvement of fertility index among children with cryptorchidism: a meta-analysis and systematic review Journal of Pediatric Surgery, October 2, 2014    Evidence Based Medicine    Review Article

13 Long-term results of combined liver-kidney transplantation for primary hyperoxaluria type 1: The French experience Liver Transplantation, October 2, 2014    Clinical Article

14 Oophorectomy versus salpingo-oophorectomy in Turner syndrome patients with Y-chromosome material: clinical experience and current practice patterns assessment Journal of Pediatric Surgery, October 2, 2014    Review Article

15 WNT5A has anti-prostate cancer effects in vitro and reduces tumor growth in the skeleton in vivo Journal of Bone and Mineral Research, October 2, 2014    Clinical Article

16 Microvascular endothelial dysfunction predicts the development of erectile dysfunction in men with coronary atherosclerosis without critical stenoses Coronary Artery Disease, October 2, 2014    Clinical Article

17 Calcium-sensing-related gene mutations in hypercalcaemic hypocalciuric patients as differential diagnosis from primary hyperparathyroidism: Detection of two novel inactivating mutations in an Italian population Nephrology Dialysis Transplantation, October 2, 2014    Clinical Article

18 Laser endoureterotomy and endopyelotomy: An update World Journal of Urology, October 2, 2014    Review Article

19 Effect of work-related factors on lower urinary tract symptoms in nurses and secretaries LUTS: Lower Urinary Tract Symptoms, October 2, 2014    Clinical Article

20 Long-term outcomes following bladder augmentation in children with neurogenic bladder Current Bladder Dysfunction Reports, October 2, 2014    Clinical Article

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Highlights in Urology

3-month PSA is a predictor of BCR-free survival after radical prostatectomy

As reported in the International Journal of Clinical Oncology, the 5-year biochemical recurrence (BCR)-free survival rate is significantly higher in patients with a 3-month PSA level < 0.010 ng/ml compared to patients with a 3-month PSA level between 0.010 and 100 ng/ml (92.6% vs. 57.4%). Amongst 174 men who underwent radical prostatectomy for clinically localized prostate cancer, 18.4% had a BCR and the median time to BCR was 16 months.

PCA3 useful for early diagnosis of prostate cancer

Based on a meta-analysis reported in the Chinese Medical Journal, prostate cancer antigen 3 (PCA3) can be used for the early diagnosis of prostate cancer and to avoid unnecessary biopsies, with a sensitivity of 0.82, a specificity of 0.962, a positive likelihood ratio of 2.39, a negative likelihood ratio of 0.51, and a diagnostic odds ratio of 4.89.

GALNT4 predicts survival in patients with ccRCC

As reported in the Journal of Urology, N-acetylgalactosaminyltransferase 4 (GALNT4) levels are decreased in tumor specimens from patients with clear cell renal cell carcinoma (ccRCC; n=104) compared to peritumoral specimens. Decreased expression of GALNT4 is associated with poor OS (OR=3.08) and RFS (OR=2.17). Further, GALNT4 is negatively correlated with tumor size, necrosis, and TNM stage.

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