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See Latest ArticlesNovel Therapeutic Targets for Prevention and Therapy of Sepsis Associated Acute Kidney Injury
Current Drug Targets, 11/10/09
Pelte CH et al. – Multiple agents have been shown in pre–clinical studies to ameliorate SA–AKI, but there are no interventions currently available for the treatment of SA–AKI. Promising agents that are in development include toll–like receptor inhibition, IL–10 augmentation, modulators of the protein C pathway, and mesenchymal stem cell mediated therapeutics. The aim of this review is to review the pathophysiology of SA–AKI and the therapeutic interventions that are under development to treat this complex and morbid disease.
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