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HPV-negative Vulvar Intraepithelial Neoplasia (VIN) With Basaloid Histologic Pattern: An Unrecognized Variant of Simplex
American Journal of Surgical Pathology , 10/29/09
Ordi J et al. – Simplex, HPV–negative VIN may occasionally have basaloid morphology. Immunostaining for p16INK4a and p53 protein may be helpful in the identification of these lesions and the differential diagnosis with classic, HPV–positive basaloid VIN.
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