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Hypoxia and Myocardial Remodeling in Human Cardiac Allografts: A Time-course Study
The Journal of Heart and Lung Transplantation, 10/28/09
Gramley F et al. – In cardiac allografts, extensive and progressive tissue remodeling is present. Hypoxia may play a role in this process by up–regulating HIF1(alpha) and leading to differential regulation of pro–angiogenic signals.
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