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Antimicrobial prophylaxis in colorectal surgery: focus on ertapenem
Therapeutics and Clinical Risk Management, 10/16/09
De Lalla F – Data that directly compares ertapenem with other antimicrobial regimen effective in preventing SSIs following colorectal surgery are lacking; furthermore, the possible risk of promotion of carbapenem resistance associated with widespread use of ertapenem prophylaxis as well as the ertapenem effects on the intestinal gut flora are of concern.
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