Surgery Medical News about Blood Transfusion liver resection

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Cardiopulmonary interventions to decrease blood loss and blood transfusion requirements for liver resection
Cochrane Reviews, 10/26/09

Gurusamy KS et al. – This review included nine trials with 587 patients. None of the interventions seem to decrease peri–operative morbidity or offer any long–term survival benefit. Haemodilution shows promise in the reduction of blood transfusion requirements in liver resection surgery. However, there is a high risk of type I (erroneously concluding that an intervention is beneficial when it is actually not beneficial) and type II errors (erroneously concluding that an intervention is not beneficial when it is actually beneficial) because of the few trials included, the small sample size in each trial, and the high risk of bias. Further randomised clinical trials with low risk of bias and random errors assessing clinically important outcomes such as peri–operative mortality are necessary to assess any cardiopulmonary interventions aimed at decreasing blood loss and blood transfusion requirements in liver resections. Trials need to be designed to assess the effect of a combination of different interventions in liver resections.

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