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Conversion from a calcineurin inhibitor to everolimus therapy in maintenance liver transplant recipients: A prospective, randomized, multicenter trial
Liver Transplantation, 10/01/09
Simone PD et al. – The data demonstrate that everolimus allows for discontinuation or a major reduction of CNI exposure in liver allograft recipients suffering CNI–related renal dysfunction without a loss of efficacy. Trials targeting earlier conversion post–transplantation are required to confirm the efficacy and safety of everolimus for improving renal function after liver transplantation.
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