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Homeostasis of the epidermal barrier layer: A theory of how occlusion reduces hypertrophic scarring
Wound Repair and Regeneration, 09/16/09
O'Shaughnessy KD et al. – Hypertrophic scarring was reduced regardless of occlusive method used. Furthermore, repeated disruption of the permeability barrier by tape stripping led to an increase in scarring. Ultrastructural analysis suggests that occluded wounds may be in an advanced state of wound repair. Occlusion may mediate its effects through establishing homeostasis of the epidermal barrier layer.
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