Surgery Medical News about dobutamine

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The effect of dobutamine on blood flow of free tissue transfer flaps during head and neck reconstructive surgery
Anaesthesia, 09/08/09

Scholz A et al. – In view of the controversy over the use of inotropes in free tissue transfer surgery, the authors assessed the effect of different intra–operative dobutamine infusion rates on blood flow in the anastomosed recipient artery. Both mean and maximum blood flow increased significantly in the anastomosed artery at dobutamine infusions of 4 and 6 microg.kg^?1.min^?1 and this was accompanied by increased cardiac output. This may improve free flap perfusion.

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