Surgery Medical News about post-operative intravenous oxycodone; CYP2D6 genotype

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Impact of the CYP2D6 genotype on post-operative intravenous oxycodone analgesia
Acta Anaesthesiologica Scandinavica, 09/03/09

Zwisler ST et al. – This study showed for the first time in patients that the oxymorphone formation depends on CYP2D6, but the authors found no difference in the post–operative analgesic effect of intravenous oxycodone between the two CYP2D6 genotypes.

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