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Safety and Efficacy of Tranexamic Acid Compared With Aprotinin in Thoracic Aortic Surgery With Deep Hypothermic Circulatory Arrest
Journal of Cardiothoracic and Vascular Anesthesia, 09/03/09
Nicolau–Raducu R et al. – Aprotinin appeared more effective in reducing blood product use after thoracic aortic surgery in this limited cohort. Aprotinin use also appeared to be associated with postoperative renal dysfunction. The choice of antifibrinolytic appeared to not be associated with cardiac, neurologic, or respiratory outcomes or survival after thoracic aortic surgery requiring DHCA.
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