Surgery Medical News about pituitary adenoma

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Incidence, clinical manifestations, and course of water and electrolyte metabolism disturbances following transsphenoidal pituitary adenoma surgery: a prospective observational study
Journal of Neurosurgery, 09/09/09

Kristof RA et al. – Water and electrolyte disturbances occurred in the majority of patients undergoing transsphenoidal adenomectomy and were usually transient. Diabetes insipidus is more frequent than hyponatremia. Diabetes insipidus usually occurs during the 1st postoperative day and resolves in the majority of cases within 10 days. In few patients, DI may persist and require therapy with ADH analogs. Hyponatremia usually occurs at the end of the 1st postoperative week and resolves in most cases within 5 days. Very few patients will need treatment other than fluid–intake restriction to avoid serious complications. Thus, careful monitoring of the WEDs in patients undergoing transsphenoidal pituitary adenoma surgery is mandatory for the first 10 postoperative days.

Signalling Pathway Alterations in Pituitary Adenomas: Involvement of Gsalpha, cAMP and Mitogen-Activated Protein Kinases
Journal of Neuroendocrinology, 11/03/09 Relevance Score: 68%

Regulation of Pituitary Function by Cytokines
Hormone Research, 10/27/09 Relevance Score: 67%

Apoplexy in non functioning pituitary adenoma after one dose of leuprolide as treatment for prostate cancer
Pituitary, 10/29/09 Relevance Score: 66%

Pituitary metastasis of Merkel cell carcinoma
Journal of Neuro-Oncology, 10/28/09 Relevance Score: 66%

Predicting Recurrence of Nonfunctioning Pituitary Adenomas
Journal of Clinical Endocrinology and Metabolism, 10/15/09 Relevance Score: 66%