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Endobronchial Ultrasound as a Diagnostic Tool in Patients With Mediastinal Lymphadenopathy
Annals of Thoracic Surgery, 09/01/09

Gilbert S et al. – Diagnostic performance data support the clinical usefulness of EBUS in the evaluation of patients with a radiographically abnormal mediastinum. It should be considered complementary to mediastinoscopy rather than substitutive.

Exclusive Author Commentary
Sebastien Gilbert MD, 09/01/09

All patients in our review had at least one mediastinal lymph node station that was abnormal on CT and/or CT/PET scan. The use of EBUS to obtain FNA of mediastinal lymph nodes is likely to decrease the number of surgical procedures (i.e. mediastinoscopy) needed. When mediastinal lymphadenopathy is due to malignant disease, the consequences of a false-negative diagnostic test may be serious (e.g.: suboptimal timing of surgical resection, delay in the delivery of definitive chemoradiation). Therefore, the false-negative rate is a key attribute of any diagnostic test used to determine lymph node status in the mediastinum. There is some overlap in the published false-negative rates of mediastinoscopy (1.6-8.8%) and EBUS (6.2-13%). Based on our data, these two approaches certainly appear to be complementary. Close collaboration between radiologists, pulmonologists, medical oncologists and thoracic surgeons remains of the essence in the management of these patients.

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Demystifying abdominal ultrasound
Australian Family Physician, 10/06/09 Relevance Score: 94%

Ultrasound guidance for peripheral nerve blockade
Cochrane Reviews, 10/12/09 Relevance Score: 93%

Ultrasound of Focal Salivary Gland Lesions
Ultrasound, 10/21/09 Relevance Score: 91%

Abdominal Fat in Children Measured by Ultrasound and Computed Tomography
Ultrasound in Medicine and Biology, 10/06/09 Relevance Score: 90%

Targeted Ultrasound of the Breast in Women With Abnormal MRI Findings for Whom Biopsy Has Been Recommended
American Journal of Roentgenology, 10/05/09 Relevance Score: 90%