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Brown MA et al. – It is usually seen in association with mucin–producing hepatobiliary and pancreatic tumors. Neoplastic transformation of these tumors can range from low–grade dysplasia to invasive adenocarcinoma. Mucobilia usually presents with signs and symptoms of biliary obstruction, which may span from jaundice to cholangitis with progression to septic complications in severe cases. Occurrence of hepatolithiasis has also been attributed to mucobilia, which raises the concern of an increased risk for the development of cholangiocarcinoma.

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