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Successful hepatitis B vaccination in liver transplant recipients with donor-specific hyporesponsiveness
Transplant International, 08/14/09
Tahara H et al. – Patients showing a donor–specific hyporesponse with a well–maintained response to the third–party stimulus always achieved a sustained immune response to the vaccine, whereas patients showing a hyporesponse to both the donor and the third–party stimulus were unable to do so. Thus, inducing an anti–donor–specific immunosuppressive status by minimizing immunosuppression should enable post–transplant HBV vaccination to be a promising prophylactic strategy.
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