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Premedication with Sublingual Morphine Sulphate in Abdominal Surgery
Clinical Drug Investigation, 07/24/09
Campiglia L et al. – Treatment with analgesics before surgery may be effective in reducing post–operative pain. This approach is defined as pre–emptive analgesia and recent reviews show conflicting results...In patients undergoing elective abdominal surgery, premedication with sublingual morphine sulphate results in a better control of post–operative pain, compared to premedication with sublingual midazolam. The beneficial effect of pre–operative sublingual morphine sulphate was apparent in the immediate post–operative period and was sustained over the 48–hour assessment period.
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