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See Latest ArticlesBreast cancer susceptibility variants alter risks in familial disease
Journal of Medical Genetics, 07/23/09
Latif A et al. – This study confirms that susceptibility variants in FGFR2, TOX3, MAP3K1, and on chromosome 8q are all associated with increased risk of cancer in individuals with a family history of breast cancer, whereas CASP8 is protective in this context. The level of risk is dependent upon the strength of the family history and the presence of a BRCA1/2 mutation and contributes to the understanding of the use of these variants in clinical risk prediction.
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The American Journal of Surgery, 12/11/09
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