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See Latest ArticlesParathyroid surgery and methylene blue: A review with guidelines for safe intraoperative use
The Laryngoscope, 07/15/09
Pollack G et al. - Methylene blue has been used to help facilitate parathyroid surgery for over 30 years. Its use has been widely considered both safe and cost effective. Twenty-six cases of a toxic metabolic encephalopathy, however, have been reported with its use. As a result, some surgeons have stopped using this technique altogether. It is now known that methylene blue is a monoamine oxidase inhibitor. When combined with drugs that increase central serotonin neurotransmission, serotonin toxicity results.
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