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Ketamine attenuates post-operative cognitive dysfunction after cardiac surgery
Acta Anaesthesiologica Scandinavica, 07/10/09
Hudetz JA et al. - Post-operative cognitive dysfunction (POCD) commonly occurs after cardiac surgery. Ketamine exerts neuroprotective effects after cerebral ischemia by anti-excitotoxic and anti-inflammatory mechanisms. Ketamine attenuates POCD 1 week after cardiac surgery and this effect may be related to the anti-inflammatory action of the drug.
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