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Basic fibroblast growth factor induces down-regulation of -smooth muscle actin and reduction of myofibroblast areas in open skin wounds
Wound Repair and Regeneration, 07/22/09
Ishiguro S et al. – The current investigation identified bFGF as a potent stimulator for the reduction of the myofibroblastic area in vivo, presumably because of its effects on the down–regulation of alpha-SMA expression as well as rapid induction of apoptosis in myofibroblasts.
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