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Activation of latent transforming growth factor-(beta)1 by nitric oxide in macrophages: Role of soluble guanylate cyclase and MAP kinases
Wound Repair and Regeneration, 07/22/09

Metukuri MR et al. – The findings suggest that NO activates latent TGF–(beta)1 via activation of sGC and generation of cGMP and separately via MAP kinase activation, and may shed insight into the mechanisms by which both cGMP production and MAP kinase activation enhance wound healing.

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