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The role of myeloperoxidase in the pathogenesis of postoperative adhesions
Wound Repair and Regeneration, 07/22/09
Saed GM et al. – Silencing iNOS reduced type I collagen and transforming growth factor–beta in adhesion fibroblasts, but to a lesser extent in peritoneal fibroblasts. These studies identify MPO and iNOS as key enzymes in the cellular response to hypoxia and consequent development of tissue fibrosis.
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