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See Latest ArticlesPreoperative radiotherapy has no value for patients with T2-3, N0 adenocarcinomas of the rectum
Digestive Surgery, 07/08/09
Ferenschild FTJ et al. – Study concludes that the preoperative radiotherapy does not seem to be of significant importance in patients with T2-3, N0 rectal cancer regarding local recurrence and survival. These pts should be treated with surgery alone.
Methods- Aim was to review the benefit of radiotherapy in T2 and T3, N0 rectal cancer pts
- 103 pts with T2-3, N0 rectal cancer were identified
- Time to local recurrence, distant metastases and overall survival were evaluated
- Median f/u was 4.3 yrs
- 5-year local control rate was 94%
- 5-year overall survival was 65%
- 5-year disease-free survival rate was 82%
- Preoperative radiotherapy did not show any statistical differences
- Abdominal perineal resection and T3 tumors negatively influenced OS
- Advanced age was of significant importance in OS
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