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Comparison of clinical risk scores predicting prognosis after resection of colorectal liver metastases
Journal of Surgical Oncology, 07/07/09

Merkel S et al. - In a study to compare the risk scores of Fong et al., Nordlinger et al., and the TNM classification of colorectal liver metastases proposed by the UICC, the study found the clinical risk score developed by Fong et al. to be a reliable preoperative prognostic tool for selecting pts for surgical resection of colorectal liver metastases.

Methods

Data from 282 consecutive pts undergoing 303 liver resections for metastatic colorectal cancer at the Department of Surgery, University of Erlangen were analyzed.
Median follow-up time was 34 mos.
A curative (R0) resection was performed in 92% of the pts.

Results

Applying the clinical risk score of Fong with preoperative data identified 3 risk groups.
Survival rates between low risk (n=22) and intermediate risk (n=222) diverged.
Survival rates between intermediate risk and high risk (n=59) differed significantly.
Using the risk scoring system of Nordlinger, pts were divided into 2 risk groups, ie, low risk (n=218) and intermediate risk (n=68).
Significant differences in survival between the groups were noted.
Applying clinical TNM classification of colorectal liver metastases revealed no significant differences in survival between risk groups.

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