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Liver resection for metastatic colorectal cancer in the presence of extrahepatic disease
Annals of Surgical Oncology, 06/29/09

Carpizo DR et al. - In a study to assess the use of liver resection for metastatic colorectal cancer (mCRC) in the presence of extrahepatic disease (EHD), there appears to be a role for surgery in highly selected pts with a single site of EHD amenable to complete resection. Unlike pts with liver-only disease, however, the goals of surgery must not be viewed as potentially curative.

Methods

This review was restricted to published data in the English language identified by searches of MEDLINE and Pubmed databases as well as reference lists of recent review articles on subjects of surgery for mCRC.

Results

5-yr survival after resection is worse than in pts with liver-only disease but approximates the survival rates seen in pts with resected liver-only metastases in the era prior to the use of modern chemotherapy.
Recurrence occurs in the great majority of pts.

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Cancer Epidemiology, Biomarkers & Prevention, 10/28/09 Relevance Score: 72%

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Colorectal Disease, 10/19/09 Relevance Score: 71%

trans-Fatty acid consumption and its association with distal colorectal cancer in the North Carolina Colon Cancer Study II
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Association of clinicopathological features with UbcH10 expression in colorectal cancer
Journal of Cancer Research & Clinical Oncology, 10/01/09 Relevance Score: 70%