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Epithelial Functions of the Residual Bowel After Surgery for Necrotising Enterocolitis in Human Infants
Journal of Pediatric Gastroenterology and Nutrition, 06/26/09
Schaart MW et al. - Residual bowel after resection for acute NEC shows a disturbed epithelial proliferation/differentiation balance. Acute NEC was associated with downregulation of distinct enterocyte-specific proteins. Because of goblet cell and Paneth cell loss in acute NEC, mucosal barrier, and defense functions may be impaired.
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