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Epithelioid-cell Myofibroblastoma of the Breast: Expanding the Morphologic Spectrum
American Journal of Surgical Pathology , 06/26/09
Magro G - This study emphasizes that epithelioid-cell MFB may be a diagnostic challenge, especially when evaluating needle core biopsies. Immunohistochemistry, revealing a variable coexpression of vimentin, desmin, (alpha)-smooth muscle actin, CD34, bcl-2 protein, CD99, CD10, estrogen/progesterone/androgen receptors, is crucial in confirming the diagnosis. Awareness of epithelioid-cell MFB is important to avoid a misdiagnosis of malignancy.
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