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Integrin and Matrix Metalloproteinase Expression in Human Carotid Plaque
Journal of Surgical Research, 06/26/09

Murillo CA et al. - The decreased integrin expression and protease activity in restenotic lesions versus primary carotid plaques suggests that the neointimal lesions were in a quiescent phase. These alterations in protein expression and protease activity demonstrate the importance of proteinase/inhibitor imbalance in regulating plaque remodeling.

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