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Different Tissue Distribution of Paclitaxel With Intravenous and Intraperitoneal Administration
Journal of Surgical Research, 06/26/09
Soma D et al. - Compared with i.v. administration, paclitaxel concentration was maintained at a high level in the whole body by i.p. administration. Repeated i.p. paclitaxel can produce more marked clinical effects than i.v. administration for metastatic lymph nodes and primary lesions as well as peritoneal dissemination.
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