Your Article Summary
See Latest ArticlesLiberal selection criteria for liver transplantation for hepatocellular carcinoma
British Journal of Surgery, 06/24/09
Muscari F et al. - In a study to compare the safety and feasibility of new, more liberal, selection criteria—no more than 5 tumours, with the largest tumour no greater than 5 cm (5/5 criteria)—with classical criteria, it appears that use of the more liberal 5/5 criteria for selecting pts for liver transplantation results in similar disease-free and overall survival rates to classical criteria.
Methods- Data from operations performed in 1990-2005 were extracted from preoperative radiological findings and postoperative specimen analyses, and 4 groups were constructed: Paul Brousse, Milan, University of California, San Francisco (UCSF), and 5/5 criteria.
- A fifth group comprised pts whose tumour load exceeded the 5/5 criteria.
- Survival and recurrence rates were compared.
- For the 110 pts in the study, survival rates (overall and disease-free) were 72.8 and 66.8% at 5 and 10 yrs respectively, with a 5.5% recurrence rate.
- 5-yr survival rate was 65, 77, 68 and 77% for Paul Brousse, Milan, UCSF, and 5/5 preoperative radiological criteria, with recurrence rates of 4, 4, 3 and 3%, respectively.
- On multivariable analysis, the only factor that influenced survival was tumour load in excess of the 5/5 criteria.
Related Articles
Aerosolized vancomycin for the treatment of MRSA after lung transplantation
Respirology, 11/10/09
Relevance Score: 94%
Pre-transplant lung function is predictive of survival following pediatric bone marrow transplantation
Pediatric Blood & Cancer, 11/05/09
Relevance Score: 94%
Soluble CD30 Levels in Recipients Undergoing Heart Transplantation Do Not Predict Post-transplant Outcome
The Journal of Heart and Lung Transplantation, 10/28/09
Relevance Score: 94%
Factors influencing liver transplant length of stay at two large-volume transplant centers
Liver Transplantation, 11/03/09
Relevance Score: 93%
Fulminant Hepatic Failure due to Varicella Zoster in a Heart Transplant Patient: Successful Liver Transplant
The Journal of Heart and Lung Transplantation, 10/28/09
Relevance Score: 93%
Today in Hepatobiliary/Pancreas...keeping you current
Receive free subspecialty "5-minute updates" via email
Isolated recurrence of distal adenocarcinoma of the extrahepatic bile duct on a draining sinus scar after curative resection: Case Report and review of the literature
World Journal of Surgical Oncology, 12/16/09
Laparoscopic Liver Resection for Hepatocellular Carcinoma in the Left Liver: Pringle Maneuver Versus Tourniquet Method
World Journal of Surgery, 12/16/09
Assessment of severity of acute pancreatitis according to new prognostic factors and CT grading
Journal of Hepato-Biliary-Pancreatic Surgery, 12/16/09
Today in Surgical Oncology...keeping you current
Receive free subspecialty "5-minute updates" via email
Surveillance and treatment for second primary cancer in the gastric tube after radical esophagectomy
Surgical Endoscopy, 12/16/09
Clinical outcome of newly diagnosed Crohns disease: a comparative, retrospective study before and after infliximab availability
Alimentary Pharmacology and Therapeutics, 12/16/09
Regional lymph node metastasis and locoregional recurrence of rectal carcinoma in the era of TNM surgery. Implications for treatment decisions
International Journal of Colorectal Disease, 12/16/09
Today in Transplantation...keeping you current
Receive free subspecialty "5-minute updates" via email
Effect of Liver Transplantation on Spleen Size, Collateral Veins, and Platelet Counts
World Journal of Surgery, 12/16/09
Rapid assessment and safe management of severe pulmonary hypertension with milrinone during orthotopic liver transplantation
Clinical Transplantation, 12/16/09
Indications for combined liver and kidney transplantation: propositions after a 23-yr experience
Clinical Transplantation, 12/16/09