Surgery Medical News about GI Cancer

Become a Member Today!
Register

Most Viewed Abstracts

1. Report Shows Shift in Starting Salaries for Physicians

2. Taxane-based combinations as adjuvant chemotherapy of early breast cancer: a meta-analysis of randomized trials

3. Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer

4. 2008 Exclusive Survey—Earnings: Good news for primary care income

5. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer

Your Article Summary

See Latest Articles

(Click the title below to leave the MDLinx Network and go to the Journal's Website)

Leucocyte depletion of perioperative blood transfusion does not affect long-term survival and recurrence in patients with gastrointestinal cancer
British Journal of Surgery, 06/24/09

Lange MM et al. - In a study to evaluate the long-term effect of transfusion with leucocyte-depleted (LD) blood in pts with gastrointestinal (GI) cancer, it appears that leucocyte depletion is not associated with better long-term survival and lower recurrence rates in pts with GI cancer.

Methods

The Transfusion Associated Complications = Transfusion Induced Complications? (TACTIC) study is a trial evaluating the short-term benefits of LD vs non-LD red blood cell (RBC) transfusions.
The present study evaluated 5-yr survival and cancer recurrence among 512 pts with GI cancer included in the TACTIC study.

Results

89.2% of pts had a primary tumour and 79.7% underwent surgery with curative intent; 243 pts received perioperative RBC transfusion (median 3 units).
5-yr overall survival rate of pts with any type of GI cancer was 50.8% in the LD group and 45.8% in the non-LD group.
Corresponding 5-yr disease-free survival rates were 60.0 and 56.6%, and recurrence rates 32.9 and 34.3%.

<< Previous
Microwave coagulation therapy for hepatic tumors: Review of the...

Next >>
Usefulness in NOTES of an intra-abdominal antifogging wireless...