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Leucocyte depletion of perioperative blood transfusion does not affect long-term survival and recurrence in patients with gastrointestinal cancer
British Journal of Surgery, 06/24/09
Lange MM et al. - In a study to evaluate the long-term effect of transfusion with leucocyte-depleted (LD) blood in pts with gastrointestinal (GI) cancer, it appears that leucocyte depletion is not associated with better long-term survival and lower recurrence rates in pts with GI cancer.
Methods- The Transfusion Associated Complications = Transfusion Induced Complications? (TACTIC) study is a trial evaluating the short-term benefits of LD vs non-LD red blood cell (RBC) transfusions.
- The present study evaluated 5-yr survival and cancer recurrence among 512 pts with GI cancer included in the TACTIC study.
- 89.2% of pts had a primary tumour and 79.7% underwent surgery with curative intent; 243 pts received perioperative RBC transfusion (median 3 units).
- 5-yr overall survival rate of pts with any type of GI cancer was 50.8% in the LD group and 45.8% in the non-LD group.
- Corresponding 5-yr disease-free survival rates were 60.0 and 56.6%, and recurrence rates 32.9 and 34.3%.
Today in Hernia/GI...keeping you current
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Complicated appendicitis in children: is laparoscopic appendectomy appropriate? A comparative study with the open appendectomy
Journal of Pediatric Surgery, 10/26/09
Treatment of Barretts esophagus with high-grade dysplasia and intramucosal adenocarcinoma
Expert Review of Gastroenterology & Hepatology, 10/13/09
A novel, easy, non-operative method of treating prolapsed colostomy
Pediatric Surgery International, 10/14/09
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Surgical management of the axilla: do intramammary nodes matter
The American Journal of Surgery, 10/07/09
Incidence of perioperative myocardial infarction and of 2-year mortality in 577 elderly patients undergoing noncardiac vascular surgery treated with and without statins
Archives of Gerontology and Geriatrics, 10/19/09
Nonoperative Management of Blunt Abdominal Trauma: Have We Gone Too Far
Surgical Infections, 11/02/09
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Original contribution: surgeon recommendations and receipt of mastectomy for treatment of breast cancer
JAMA, 10/28/09
Extended lymphadenectomy versus conventional surgery for rectal cancer: a meta-analysis : The Lancet Oncology
The Lancet Oncology - Online First, 10/23/09
Surgical management of colorectal liver metastases
Community Oncology , 10/09/09
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