Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. Taxane-based combinations as adjuvant chemotherapy of early breast cancer: a meta-analysis of randomized trials 3. Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer 4. 2008 Exclusive Survey—Earnings: Good news for primary care income 5. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
Your Article Summary
See Latest ArticlesEvidence for using clopidogrel alone or in addition to aspirin in post coronary artery bypass surgery patients
The American Journal of Cardiology, 06/22/09
Patel JH et al. – Summarized data based on subgroup analyses, surrogate endpoints, and observational cohort studies fail to shhow a clear beneficial effect of clopidogrel alone or in combination with aspirin on clinical outcomes after coronary artery bypass grafting (CABG).
Methods- Systematic review of published research to determine whether clopidogrel use after CABG is based on good trial data
- Review of studies reporting safety and/or efficacy data for clopidogrel use with/without aspirin after on-/off-pump CABG
- Inclusion criteria met by 14 studies: 11 reported trials; 3 ongoing trials
- Subgroup retrospective analyses of previously reported large trials of pts (1 pt) presenting with acute coronary syndromes or pts (3) with stable coronary artery disease did not show a clear clinical benefit of clopidogrel when given in addition to aspirin after CABG
- Trend toward increased major and minor bleeding after use of clopidogrel plus aspirin
- Quality inferior for meaningful conclusions: 2 small prospective trials providing data on surrogate endpoints and 5 small trials involving off-pump CABG pts
Today in Cardiac Surgery...keeping you current
Receive free subspecialty "5-minute updates" via email
Comparison of Two-Year Outcomes in Patients Undergoing Isolated Coronary Artery Bypass Grafting With and Without Peripheral Artery Disease
The American Journal of Cardiology, 11/09/09
On-Pump versus Off-Pump Coronary-Artery Bypass Surgery
New England Journal of Medicine, 11/05/09
Dexmedetomidine use in a pediatric cardiac intensive care unit: Can we use it in infants after cardiac surgery
Pediatric Critical Care, 11/11/09
Today in Clinical Pharmacology...keeping you current
Receive free subspecialty "5-minute updates" via email
Current therapies to shorten postoperative ileus
Cleveland Clinic Journal of Medicine, 11/04/09
Prophylactic Vasopressin in Patients Receiving the Angiotensin-Converting Enzyme Inhibitor Ramipril Undergoing Coronary Artery Bypass Graft Surgery
Journal of Cardiothoracic and Vascular Anesthesia, 11/02/09
Interventions for prevention of post-operative recurrence of Crohn's disease
Cochrane Reviews, 10/27/09
Sponsor
Article Search
Sponsor