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Carter JT et al. - This is one of the largest series of neuroendocrine tumors of the ampulla. Preoperative biopsy was accurate, but computed tomographic scans were insensitive in detecting nodal metastases. Unlike duodenal carcinoid tumors, hypersecretion syndromes were absent and small tumor size did not preclude locoregional metastases. Tumor grade predicted survival. The authors recommend pancreaticoduodenectomy for this disease, with local resection reserved for mobile, superficial lesions.

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