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See Latest ArticlesReoperation for Intracranial Hypertension in TWIST1-Confirmed Saethre-Chotzen Syndrome
Plastic and Reconstructive Surgery, 06/02/09
Woods RH et al. - Despite standard surgical intervention, patients with Saethre-Chotzen syndrome have a high rate of recurrent intracranial hypertension necessitating further surgical expansion. All patients with either bicoronal synostosis or unicoronal synostosis with syndromic features should be screened for TWIST1 mutations, as this confers a greater risk than nonsyndromic synostosis of the same sutures. Regular follow-up throughout the childhood years is essential.
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