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GATA3 inhibits breast cancer growth and pulmonary breast cancer metastasis
Oncogene, 06/03/09

Dydensborg AB et al. - The data correlate with microarray data from human breast cancer patients, showing a strong correlation between high GATA3 expression and absence of metastases specifically to the lungs. The authors conclude that GATA3 inhibits primary breast tumor outgrowth and reduces lung metastatic burden by regulating key genes involved in metastatic breast tumor progression.

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