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When Is Prophylactic Thyroidectomy Indicated for Patients with the RET Codon 609 Mutation
Annals of Surgical Oncology, 06/01/09
Calva D et al. - The youngest patient with C609Y RET mutation and MTC was 21 years old, and the youngest patient with CCH was 15 years old at diagnosis. These data suggest that patients with RET C609Y mutations can delay thyroidectomy until 10–15 years of age, with annual calcitonin screening prior to thyroidectomy.
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