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Cancer in obese women: Potential protective impact of bariatric surgery
Journal of the American College of Surgeons, 06/01/09

McCawley GM et al. - Breast and endometrial cancers remain the most common types in obese women and may occur at young ages; bariatric surgery may decrease cancer development in obese women.

Methods

Study to report on:
- types of cancer in morbidly obese women undergoing bariatric surgery and
- compare these with types of cancer in obese women w/o surgery
Bariatric surgery database identified women who underwent operations between 1990-2006 at the Univ. of Virginia
Morbidly obese pts not undergoing bariatric surgery were used for comparison

Results

1,482 women had bariatric surgery, 3.6% were diagnosed with cancer
Most common cancer site was the breast followed by the endometrium and the cervix
Mean age at cancer diagnosis was 39.4 yrs
Most cancers were diagnosed before the bariatric surgery
Bariatric surgery pts with cancer were older than noncancer pts at time of surgery
Compared to obese women who had not undergone bariatric surgery, the surgery pts had fewer cancers, were younger, and were younger at cancer diagnosis
Most frequent cancers in the control obese women: endometrial, ovarian, and breast cancer
Both groups of obese women with endometrial, breast, ovarian, and colorectal cancers were younger at diagnosis compared with Virginia Cancer Registry means

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