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Effect of smoking, abstention, and nicotine patch on epidermal healing and collagenase in skin transudate
Wound Repair and Regeneration, 05/26/09
Sørensen LT et al. - The authors conclude that smoking attenuates epidermal healing and may enhance extracellular matrix degradation. Three months of abstinence from smoking does not restore epidermal healing, whereas 4 weeks of abstinence normalizes suction blister MMP-8 levels. These findings suggest sustained impaired wound healing in smokers and potential reversibility of extracellular matrix degradation.
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